Almost 2 million Americans abuse or are dependent on prescription opioids.  12.5 million Americans misuse prescription pain relievers.  As many as 1 in 4 people who receive prescription opioids long term for non-cancer pain in primary care settings struggle with addiction. 

On a given day, in the United States:

-   More than 525,000 opioid prescriptions are dispensed.

-   5,750 people initiate non medical use of prescription opioids.

-   Over 3,800 prescription opioids adverse events emergency room (ER) visits.

-   61 people, most between 25 to 54 years old, die from a prescription opioid overdose.

Over 168,000 adolescents (12 to 17 years old) have an addiction to prescription pain relievers.



67% of opioids used nonmedically are supplied by friends or relatives - 53.0% for free, 14.6% were bought or taken from a friend/relative.


ACCOY's overdose, misuse, abuse, diversion and accidental ingestion deterrent opioids are for chronic pain patients that do not respond to other pain therapy.  ACCOY opioids will be the only opioids that address all the prescription Opioid epidemic issues of concern to all the stakeholders, the CDC, DEA, NIH, the White House, state and local governments, payers, physicians, and patients.  Each ACCOY opioid represents an improved opioid/safety profile, improved pain and patient management, and a decrease in the total cost of care.

The opioid epidemic is devastating families at all income levels and, according to the White House Council of Economic Advisers (CEA), is costing in excess of $504 billion, 2.8 percent of the United States gross domestic product, in health and social costs annually.  In 2016, one in three Americans, 64 million people, filled 215 million opioid prescriptions.  This is especially alarming in light of the CDC's findings that opioid-naive patients who fill a prescription for a one day supply of opioids face a 6% risk of continuing their use of opioids for more than one year.  The CDC also found that the longer a person's first exposure to opioids, the greater the risk that he or she will continue using opioids after one, or even three years.  For example, when a person's first exposure to opioids increases from one day to 30 days, that person's likelihood of continuing to use opioids after one year increases from 6% to about 35%.  4.5 million Americans are addicted to prescription opioids.  People addicted to prescription painkillers are 40 times more likely to become addicted to heroin.  Three in four new heroin users started out misusing prescription painkillers.   


Federal, State, and payor efforts has created a second epidemic, pain patients that are unable to get adequate pain relief do to inappropriate application of opioid prescribing guidelines, restricted prescribing, physicians scared to prescribe opioids, and attempts by physicians to decrease the amound of prescribed opioid. 

Efforts to curve opioid prescribing has shifted the opioid epidemic from prescribed opioids to heroin and now to fentanyl. Simultaneously, patient and professional medical groups have organized to ensure patients who need opioids to control their pain have access to opioids.  This is going to be an increasing theme over the nest few years as a balance has to be struck between proper pain management and illicit use of prescription opioids.